|
|
vinylacetyl-CoA <=> crotonyl-CoA
|
5.3.3.3
vinylacetyl-CoA Delta-isomerase
|
–
|
K
|
|
BRENDA:
BR1
KEGG:
R03031
MetaCyc:
VINYLACETYL-COA-DELTA-ISOMERASE-RXN
|
|
|
|
(3R)-hydroxybutyryl-CoA <=> crotonyl-CoA + H2O
|
4.2.1.119
enoyl-CoA hydratase 2
4.2.1.150
short-chain-enoyl-CoA hydratase
4.2.1.17
enoyl-CoA hydratase
4.2.1.55
3-hydroxybutyryl-CoA dehydratase
4.2.1.59
3-hydroxyacyl-[acyl-carrier-protein] dehydratase
|
–
–
–
–
–
|
BMK
|
|
BRENDA:
BR433;
BS18665
KEGG:
R03027;
R05595
MetaCyc:
3-HYDROXBUTYRYL-COA-DEHYDRATASE-RXN
SABIO-RK:
2877;
5195
|
|
|
|
glutaconyl-CoA + H+ + Na+ <=> CO2 + crotonyl-CoA + Na+
|
7.2.4.5
glutaconyl-CoA decarboxylase
|
–
|
BM
|
|
BRENDA:
BR48314
MetaCyc:
RXN-19739
|
|
|
|
L-3-aminobutanoyl-CoA <=> NH3 + crotonyl-CoA
|
4.3.1.14
3-aminobutyryl-CoA ammonia-lyase
|
–
|
MK
|
|
BRENDA:
BR485
KEGG:
R03030
MetaCyc:
4.3.1.14-RXN
|
|
|
|
4-hydroxybutanoyl-CoA <=> crotonyl-CoA + H2O
|
4.2.1.120
4-hydroxybutanoyl-CoA dehydratase
|
–
|
BMK
|
|
BRENDA:
BR49128
KEGG:
R10782
MetaCyc:
RXN-8890
|
|
|
|
(2S)-ethylmalonyl-CoA + NADP+ <=> crotonyl-CoA + CO2 + NADPH
|
1.3.1.85
crotonyl-CoA carboxylase/reductase
|
–
|
BMK
|
|
BRENDA:
BR49400
KEGG:
R09291
MetaCyc:
RXN-8957
|
|
|
|
butyryl-CoA + NADP+ <=> crotonyl-CoA + NADPH + H+
|
1.3.1.10
enoyl-[acyl-carrier-protein] reductase (NADPH, Si-specific)
1.3.1.38
trans-2-enoyl-CoA reductase (NADPH)
1.3.1.39
enoyl-[acyl-carrier-protein] reductase (NADPH, Re-specific)
1.3.1.44
trans-2-enoyl-CoA reductase (NAD+)
1.3.1.8
acyl-CoA dehydrogenase (NADP+)
1.3.1.85
crotonyl-CoA carboxylase/reductase
1.3.1.86
crotonyl-CoA reductase
1.3.1.9
enoyl-[acyl-carrier-protein] reductase (NADH)
|
–
–
–
–
–
–
–
–
|
K
|
|
BRENDA:
BR49401
KEGG:
R09738
MetaCyc:
RXN-11726
SABIO-RK:
7647
|
|
|
|
glutaconyl-CoA + H+ <=> CO2 + crotonyl-CoA
|
1.3.8.6
glutaryl-CoA dehydrogenase (ETF)
6.4.1.4
methylcrotonoyl-CoA carboxylase
7.2.4.5
glutaconyl-CoA decarboxylase
|
–
–
–
|
MK
|
|
BRENDA:
BR50094
KEGG:
R03028
MetaCyc:
GLUTACONYL-COA-DECARBOXYLASE-RXN
SABIO-RK:
2878
|
|
|
|
(S)-3-hydroxybutyryl-CoA <=> H2O + crotonyl-CoA
|
1.3.8.7
medium-chain acyl-CoA dehydrogenase
4.2.1.116
3-hydroxypropionyl-CoA dehydratase
4.2.1.150
short-chain-enoyl-CoA hydratase
4.2.1.17
enoyl-CoA hydratase
|
–
–
–
–
|
BMK
|
|
BRENDA:
BR51003
KEGG:
R03026
MetaCyc:
RXN-11667;
RXN-15014
SABIO-RK:
2876
|
|
|
|
butyryl-CoA + NAD+ + reduced_ferredoxin_[iron-sulfur]_cluster <=> crotonyl-CoA + NADH + oxidized_ferredoxin
|
1.3.1.109
butanoyl-CoA dehydrogenase (NAD+, ferredoxin)
|
–
|
M
|
|
BRENDA:
BR51444
KEGG:
R11675
MetaCyc:
RXN-16834
|
|
|
|
butyryl-CoA + NAD+ <=> crotonyl-CoA + NADH + H+
|
1.3.1.44
trans-2-enoyl-CoA reductase (NAD+)
1.3.1.9
enoyl-[acyl-carrier-protein] reductase (NADH)
|
–
–
|
MK
|
|
BRENDA:
BS258558
KEGG:
R01171
MetaCyc:
RXN-12558
SABIO-RK:
1408
|
|
|
|
acetyl-CoA + crotonate <=> acetate + crotonyl-CoA
|
2.8.3
2.8.3.1
propionate CoA-transferase
2.8.3.12
glutaconate CoA-transferase
2.8.3.9
butyrate---acetoacetate CoA-transferase
|
–
–
–
–
|
M
|
|
BRENDA:
BS358828
MetaCyc:
RXN-15008
SABIO-RK:
13019
|
|
|
|
butyryl-CoA + flavin <=> crotonyl-CoA + reduced_flavodoxin
|
1.3.8.1
short-chain acyl-CoA dehydrogenase
1.3.8.4
isovaleryl-CoA dehydrogenase
1.3.8.7
medium-chain acyl-CoA dehydrogenase
1.3.8.8
long-chain acyl-CoA dehydrogenase
|
–
–
–
–
|
|
|
BRENDA:
BR36851
KEGG:
R01178
|
|
|
|
glutaryl-CoA + flavin <=> crotonyl-CoA + CO2 + reduced_flavodoxin
|
1.3.8.6
glutaryl-CoA dehydrogenase (ETF)
|
–
|
BK
|
|
BRENDA:
BR36856
KEGG:
R02488
|
|
|
|
glutaryl-CoA + FAD <=> crotonyl-CoA + CO2 + FADH2
|
1.3.8.6
glutaryl-CoA dehydrogenase (ETF)
|
–
|
K
|
|
BRENDA:
BS413390
KEGG:
R02487
SABIO-RK:
2417
|
|
|
|
butyryl-CoA + FAD <=> crotonyl-CoA + FADH2
|
1.3.3.6
acyl-CoA oxidase
1.3.8.1
short-chain acyl-CoA dehydrogenase
1.3.8.4
isovaleryl-CoA dehydrogenase
1.3.8.7
medium-chain acyl-CoA dehydrogenase
1.3.99
|
–
–
–
–
–
|
K
|
|
BRENDA:
BS414397
KEGG:
R01175
SABIO-RK:
1412
|
|
|
|
butyryl-CoA + O2 <=> crotonyl-CoA + H2O2
|
1.3.3.6
acyl-CoA oxidase
1.3.8.1
short-chain acyl-CoA dehydrogenase
|
–
–
|
B
|
|
BRENDA:
BS258730
SABIO-RK:
9597
|
|
|
|
butyryl-CoA + acceptor <=> crotonyl-CoA + reduced_acceptor
|
1.3.8.1
short-chain acyl-CoA dehydrogenase
1.3.8.4
isovaleryl-CoA dehydrogenase
1.3.8.7
medium-chain acyl-CoA dehydrogenase
1.3.99.12
2-methylacyl-CoA dehydrogenase
|
–
–
–
–
|
B
|
|
BRENDA:
BS258764
SABIO-RK:
1415
|
|
|
|
glutaryl-CoA + acceptor <=> crotonyl-CoA + CO2 + reduced_acceptor
|
1.3.8.6
glutaryl-CoA dehydrogenase (ETF)
|
–
|
|
|
BRENDA:
BS258889
SABIO-RK:
2418
|
|
|
|
crotonate + acetoacetyl-CoA <=> crotonyl-CoA + acetoacetate
|
2.8.3.9
butyrate---acetoacetate CoA-transferase
|
–
|
|
|
BRENDA:
BS358827
SABIO-RK:
11109
|
|
|
|
crotonyl-CoA + H2O <=> CoA + crotonate
|
2.3.3.13
2-isopropylmalate synthase
3.1.2.1
acetyl-CoA hydrolase
3.1.2.2
palmitoyl-CoA hydrolase
3.1.2.20
acyl-CoA hydrolase
3.1.2.23
4-hydroxybenzoyl-CoA thioesterase
|
–
–
–
–
–
|
|
|
BRENDA:
BS360746
SABIO-RK:
9663
|
|
|
|
ATP + crotonyl-CoA + HCO3- <=> ADP + phosphate + glutaconyl-CoA
|
6.4.1.4
methylcrotonoyl-CoA carboxylase
|
–
|
|
|
BRENDA:
BS369198
SABIO-RK:
13918
|
|
|
|
butyryl-CoA + 2,6-dichlorophenolindophenol <=> crotonyl-CoA + reduced_2,6-dichlorophenolindophenol
|
1.3.8.1
short-chain acyl-CoA dehydrogenase
|
–
|
|
|
BRENDA:
BS451538
SABIO-RK:
11492
|
|
|
|
cyclopropanecarboxyl-CoA <=> crotonyl-CoA
|
5.5.1
|
–
|
K
|
|
KEGG:
R07829
|
|
|
|
butyryl-CoA + oxidized_electron_transfer_flavoprotein + H+ <=> crotonyl-CoA + reduced_flavodoxin
|
1.3.8.1
short-chain acyl-CoA dehydrogenase
|
–
|
M
|
|
MetaCyc:
BUTYRYL-COA-DEHYDROGENASE-RXN
|
|
|
|
glutaryl-CoA + oxidized_electron_transfer_flavoprotein + H+ <=> crotonyl-CoA + CO2 + reduced_flavodoxin
|
1.3.8.6
glutaryl-CoA dehydrogenase (ETF)
|
–
|
|
|
MetaCyc:
GLUTARYL-COA-DEHYDROGENASE-RXN
|
|
|
|
glutaryl-CoA + 2,6-dichlorophenolindophenol <=> crotonyl-CoA + CO2 + reduced_2,6-dichlorophenolindophenol
|
1.3.8.6
glutaryl-CoA dehydrogenase (ETF)
|
–
|
|
|
BRENDA:
BS373305
|
|
|
|
glutaconyl-CoA + ferrocenium_hexafluorophosphate <=> crotonyl-CoA + CO2 + ferrocenium_hexafluorophosphate
|
1.3.8.6
glutaryl-CoA dehydrogenase (ETF)
|
–
|
|
|
BRENDA:
BS397269
|
|
|
|
crotonyl-CoA + reduced_ferredoxin <=> butyryl-CoA + oxidized_ferredoxin
|
1.3.8.1
short-chain acyl-CoA dehydrogenase
|
–
|
|
|
BRENDA:
BS428498
|
|
|
|
glutaryl-CoA + phenazine_methosulfate <=> crotonyl-CoA + CO2 + reduced_phenazine_methosulfate
|
1.3.8.6
glutaryl-CoA dehydrogenase (ETF)
|
–
|
|
|
BRENDA:
BS453882
|
|
|
|
crotonyl-CoA + L-homoserine <=> CoA + O-crotonyl-L-homoserine
|
2.3.1.31
homoserine O-acetyltransferase
|
–
|
|
|
BRENDA:
BS320795
|
|
|
|
crotonyl-CoA + reduced_flavodoxin <=> butyryl-CoA + electron_transfer_protein
|
1.3.8.1
short-chain acyl-CoA dehydrogenase
|
–
|
B
|
|
BRENDA:
BS370162
|
|
|
|
butyryl-CoA + Ferrocene <=> crotonyl-CoA + Ferrocene
|
1.3.8.1
short-chain acyl-CoA dehydrogenase
|
–
|
|
|
BRENDA:
BS396639
|
|
|
|
butyryl-CoA + ferricenium <=> crotonyl-CoA + Ferrocene
|
1.3.8.1
short-chain acyl-CoA dehydrogenase
|
–
|
|
|
BRENDA:
BS396638
|
|
|
|
crotonyl-CoA + [acyl-carrier_protein] <=> CoA + a_2-butenoyl-[acyl_carrier_protein]
|
2.3.1.39
[acyl-carrier-protein] S-malonyltransferase
|
–
|
|
|
BRENDA:
BS454906
|
|
|
|
crotonyl-CoA + [acyl-carrier_protein] <=> CoA + a_crotonyl-[acyl-carrier_protein]
|
2.3.1.85
fatty-acid synthase system
|
–
|
|
|
BRENDA:
BS455484
|
|
|
|
butyryl-CoA + phenazine_methosulfate <=> crotonyl-CoA + reduced_phenazine_methosulfate
|
1.3.8.8
long-chain acyl-CoA dehydrogenase
|
–
|
|
|
BRENDA:
BS260361
|
|
|
|
(R)-3-hydroxybutyryl-CoA <=> crotonyl-CoA + H2O
|
1.1.1.36
acetoacetyl-CoA reductase
3.3.2.12
oxepin-CoA hydrolase
|
–
–
|
B
|
|
BRENDA:
BS370747
|
|
|
|
crotonyl-CoA + O2 + 2 NADH + 2 H+ <=> butyryl-CoA + H2O2 + 2 NAD+
|
1.3.8.1
short-chain acyl-CoA dehydrogenase
|
–
|
|
|
BRENDA:
BS428497
|
|
|
|
crotonyl-CoA + 2 NADH + 2 oxidized_ferredoxin_iron-sulfur_cluster <=> butyryl-CoA + 2 NAD+ + 2 reduced_ferredoxin_iron-sulfur_cluster
|
1.3.1.109
butanoyl-CoA dehydrogenase (NAD+, ferredoxin)
|
–
|
|
|
BRENDA:
BS430813
|
|
|
|
crotonyl-CoA + 2 NADH + 2 Fd- <=> butyryl-CoA + 2 NAD+ + 2 Fd2-
|
1.3.8.1
short-chain acyl-CoA dehydrogenase
|
–
|
|
|
BRENDA:
BS440200
|
|
|
|
crotonyl-CoA + NAD+ <=> butyryl-CoA + NADH + H+
|
1.3.1.9
enoyl-[acyl-carrier-protein] reductase (NADH)
|
–
|
|
|
BRENDA:
BS404718
|
|
|
|
crotonyl-CoA + NADPH + H+ <=> butyryl-CoA + NAP+
|
1.3.1.104
enoyl-[acyl-carrier-protein] reductase (NADPH)
1.3.1.B14
|
–
–
|
|
|
BRENDA:
BS441223
|
|
|
|
glutaryl-CoA + ferrocenium_hexafluorophosphate <=> crotonyl-CoA + CO2 + ferrocenium_hexafluorophosphate
|
1.3.8.6
glutaryl-CoA dehydrogenase (ETF)
|
–
|
|
|
BRENDA:
BS397277
|
|
|
|
glutaryl-CoA + electron_transfer_protein <=> crotonyl-CoA + CO2 + reduced_electron_transfer_protein
|
1.3.8.6
glutaryl-CoA dehydrogenase (ETF)
|
–
|
|
|
BRENDA:
BS370971
|
|
|
|
glutaryl-CoA + human_electron-transfer_flavoprotein <=> crotonyl-CoA + CO2 + reduced_human_electron-transfer_flavoprotein
|
1.3.8.6
glutaryl-CoA dehydrogenase (ETF)
|
–
|
|
|
BRENDA:
BS451540
|
|
|
|
crotonyl-CoA + H2O <=> 2-hydroxybutanoyl-CoA
|
4.2.1.54
lactoyl-CoA dehydratase
|
–
|
|
|
BRENDA:
BS18744
|
|
|
|
crotonyl-CoA + NADH <=> butyryl-CoA + NADP+
|
1.3.1.8
acyl-CoA dehydrogenase (NADP+)
|
–
|
|
|
BRENDA:
BS258629-a
|
|
|
|
glutaconyl-CoA + acceptor <=> crotonyl-CoA + CO2 + reduced_acceptor
|
1.3.8.6
glutaryl-CoA dehydrogenase (ETF)
|
–
|
|
|
BRENDA:
BS258895
|
|
|
|
(2R)-2-hydroxybutyryl-CoA <=> crotonyl-CoA + H2O
|
4.2.1.54
lactoyl-CoA dehydratase
|
–
|
|
|
BRENDA:
BS18745
|
|
|
|
crotonyl-CoA + malonyl-CoA <=> 6-(2-propene)_triacetic_acid_lactone + CoA
|
2.3.1.165
6-methylsalicylic-acid synthase
|
–
|
|
|
BRENDA:
BS320578
|
|
|
|
crotonyl-CoA + electron_acceptor <=> butyryl-CoA + reduced_acceptor
|
1.3.8.1
short-chain acyl-CoA dehydrogenase
|
–
|
|
|
BRENDA:
BS388401
|
|
|
|
butyryl-CoA + flavin <=> crotonyl-CoA + reduced_acceptor
|
1.3.8.1
short-chain acyl-CoA dehydrogenase
|
–
|
|
|
BRENDA:
BS388275
|
|
|
|
butyryl-CoA + oxidized_3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium_bromide <=> crotonyl-CoA + reduced_acceptor
|
1.3.8.1
short-chain acyl-CoA dehydrogenase
|
–
|
|
|
BRENDA:
BS258809
|
|
|
|
butyryl-CoA + electron_acceptor <=> crotonyl-CoA + reduced_acceptor
|
1.3.8.1
short-chain acyl-CoA dehydrogenase
|
–
|
|
|
BRENDA:
BS258782
|
|
|
|
crotonyl-CoA + reduced_acceptor <=> butyryl-CoA + oxidized_acceptor
|
1.3.1.8
acyl-CoA dehydrogenase (NADP+)
1.3.8.1
short-chain acyl-CoA dehydrogenase
|
–
–
|
B
|
|
BRENDA:
BS370908
|
|
|
|
butyryl-CoA + pyocyanine + 2,3,5-triphenyltetrazolium_chloride <=> crotonyl-CoA + reduced_acceptor
|
1.3.8.1
short-chain acyl-CoA dehydrogenase
|
–
|
|
|
BRENDA:
BS258806
|
|
|
|
crotonyl-CoA + hydroxylamine <=> CoA + 3-methyl-5-isoxazolidinone
|
4.3.1.14
3-aminobutyryl-CoA ammonia-lyase
|
–
|
|
|
BRENDA:
BS2235
|
|
|
|
ATP + crotonate + CoA <=> AMP + diphosphate + crotonyl-CoA
|
6.2.1.17
propionate---CoA ligase
6.2.1.2
medium-chain acyl-CoA ligase
6.2.1.40
4-hydroxybutyrate---CoA ligase (AMP-forming)
6.2.1.44
3-(methylthio)propionyl---CoA ligase
|
–
–
–
–
|
|
|
BRENDA:
BS188
|
|
|
|
crotonate + butyryl-CoA <=> Butyrate + crotonyl-CoA
|
2.8.3.9
butyrate---acetoacetate CoA-transferase
|
–
|
|
|
SABIO-RK:
11123
|
|